Which category of drugs has NOT been associated with gingival enlargement?

Gingival enlargement, also known as gingival hyperplasia, is a condition characterized by an increase in the size of the gums. Several categories of drugs are known to have this side effect.

Anticonvulsants, such as phenytoin, are commonly associated with gingival enlargement. This is particularly important for dental practitioners to recognize, as patients on these medications may require diligent oral hygiene and monitoring.

Immunosuppressants, particularly drugs like cyclosporine, are also linked to gingival hyperplasia. This association is significant because immunosuppressed patients are at increased risk of oral conditions, necessitating careful management of their oral health.

Calcium channel blockers can lead to gingival enlargement as well. Medications in this class, such as nifedipine, are often prescribed for hypertension and other cardiovascular issues and have been documented as increasing the gingival tissue growth.

On the other hand, MAO inhibitors have not been commonly associated with gingival enlargement. While they may interact with other medications and have various side effects, the specific link to gingival hyperplasia is not established. Recognizing which medications do not cause this side effect helps healthcare providers to better inform patients and manage their oral health proactively. Understanding these differences